Nistatin ointment 30 g (1 oz) Нистатиновая мазь

Description

Specifications
Active ingredients
Nystatin
Manufacturer's country
Russia
Manufacturer
Biosynthesis of PAO
Release form
Ointment for external use 100 000 units/g of 30 g in an aluminum tube. Each tube together with the instructions for use is placed in a pack of cardboard.
Store in the refrigerator
Store in a place protected from light
Keep away from children
Dosage form
Homogeneous ointment from yellow to brownish-yellow color.
Composition
Active ingredient: Nystatin - 2.222 g
Excipients: anhydrous lanolin-40,000 g vaseline-up to 100 g
Special conditions
The use of ointment can be combined with the intake of nystatin inside.
If an allergic reaction occurs on the skin during and after applying the ointment, it is necessary to stop using the drug and consult a doctor.
The effect of the drug on the ability to drive vehicles and mechanisms
The drug does not affect the ability to drive vehicles, mechanisms and engage in other potentially dangerous activities that require increased concentration and speed of psychomotor reactions.
Drug interaction
With the simultaneous use of nystatin with clotrimazole, the activity of the latter decreases.
Pharmacodynamics
Polyene antifungal antibiotic. It has antifungal (fungistatic and fungicidal) activity. It has a large number of double bonds in the structure, which cause a high tropicity of the substance to the sterol formations of the cytoplasmic membrane of fungi. As a result, the molecule is embedded in the cell membrane with the formation of many channels that promote the uncontrolled transport of water, electrolytes and non-electrolytes. The cell loses its resistance to external osmotic forces and is lysed. Resistance develops very slowly.
It is active against yeast-like fungi of the genus Candida and Aspergillus. It has a fungistatic, and in large doses - a fungicidal effect.
Pharmacokinetics
It is not absorbed from the surface of the skin.
Indications
Treatment and prevention of candidiasis of the skin.
Contraindications
Hypersensitivity to the components of the drug.
With caution
Pregnancy, childhood.
Use during pregnancy and during breastfeeding
Pregnancy
Use during pregnancy is possible if the intended benefit to the mother exceeds the potential risk to the fetus or child, only after consultation with the attending physician.
Breastfeeding period
It is possible to use the drug during breastfeeding (nystatin is not absorbed from the surface of the skin), excluding the area of the mammary glands, only after consulting with your doctor.
Overdose
Due to the fact that the drug is not absorbed from the surface of the skin, the possibility of overdose is excluded. No cases of nystatin overdose have been recorded.
Side effects
Skin itching, rashes, fever, chills, allergic reactions.